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当前位置: 首页 > 产品中心 > peptide > reprocell/Stemolecule RG108/04-0001-base
商品详细reprocell/Stemolecule RG108/04-0001-base
reprocell/Stemolecule RG108/04-0001-base
reprocell/Stemolecule RG108/04-0001-base
商品编号: 04-0001-base
品牌: reprocell
市场价: ¥2700.00
美元价: 1350.00
产地: 美国(厂家直采)
公司:
产品分类: 多肽合成
公司分类: peptide
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Stemolecule RG108 is a cell-permeable small molecule that inhibits DNA methyltransferases. Treatment with RG108 results in the demethylation of genomic DNA and can reactivate epigenetically silenced tumor suppressor genes, making it a great tool for studying methlytransferase biological functions in vivo and in vitro1,2. It is particularly useful due to its non-covalent binding to the enzyme activation domain, which makes the inhibition reversible. Along with BIX01294, RG108 has been shown to improve the reprogramming efficiency of mouse embryonic fibroblasts (MEFs) into induced pluripotent stem (iPS) cells3. RG108 can potentially be used to maintain embryonic stem (ES) cells in an undifferentiated state as well as replace transcription factors in both mouse and human cell reprogramming.

品牌介绍
reprocell的hES细胞克隆和恢复补充剂(5件装)hES细胞克隆和恢复补品是1000X浓缩补品,其中含有2mM浓度的噻唑烷。hES细胞克隆和恢复补充剂可用于细胞培养的多个领域,以提高生产率和效率。向细胞培养基中添加hES细胞克隆和恢复补充剂可显着提高从单个细胞成功亚克隆的可能性1,2。该补充剂已在2 uM的工作浓度下进行了验证,但是最佳条件可能会有所不同,应由用户确定。在融化过程中添加时,该补充剂可提高恢复和解冻效率。使用hES细胞克隆和恢复补充剂还可以增加传代后的附着力。当在压力条件下与人胚胎干(hES)和人诱导的多能干(hiPS)细胞一起工作时,hES细胞克隆和恢复补充剂是提高效率的宝贵工具。